The Effect of Catecholamines and Cold Exposure on the Lipolytic Activity of Rat Heart

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Abstract
Norepinephrine or epinephrine (100-200 mg/rat subcut) has no profound influence on rat heart clearing factor lipase activity in acute experiment: the trend toward an increased activity is not statistically significant. An important increase of heart clearing factor lipase activity, however, is found, in rats exposed for 3 or 12 hours to cold environment (4[degree]C). This increase was paralleled in the 3 hours'', but not in the 12 hours'' period, by an increased level of free fatty acids in serum. These data suggest that the physiological adaptation of the heart clearing factor lipase activity is not, or only in minor part, induced through a release or norepinephrine or epinephrine.