OXYGEN SATURATION OF STERNAL MARROW BLOOD IN POLYCYTHEMIA VERA 1

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Abstract
Oxygen content, capacity, and percentage saturation of bone marrow blood were detd. in man in a group of controls and in patients with polycythemia vera, anemia, and anoxic anoxia. The percentage saturation of bone marrow blood was greater and the arterial-bone marrow blood oxygen difference was smaller in patients with polycythemia vera than in controls. This finding does not support the theory that there is a local bone marrow anoxia due to decreased blood flow in polycythemia vera, but is compatible with either increased blood flow or decreased oxygen utilization by the marrow in this disease. No significant differences were found between anemias and controls, in a small number of cases. In patients with anoxic anoxia, the percentage saturation of bone marrow blood with oxygen was lower than in the controls.
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