Permeability Characteristics of Various Intestinal Regions of Rabbit, Dog, and Monkey
- 1 January 1992
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 09 (12) , 1580-1586
- https://doi.org/10.1023/a:1015812408231
Abstract
The in vitro permeability of a series of both hydrophilic and lipophilic compounds, as defined by the octanol/water partition coefficient, was measured in four segments of rabbit, monkey, and dog...Keywords
This publication has 18 references indexed in Scilit:
- Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cellsBiochemical and Biophysical Research Communications, 1991
- Characterization of the Unstirred Water Layer in Caco-2 Cell Monolayers Using a Novel Diffusion ApparatusPharmaceutical Research, 1991
- Mechanism of Acyclovir Uptake in Rat JejunumPharmaceutical Research, 1990
- POLYETHYLENE-GLYCOL-900 PERMEABILITY OF RAT INTESTINAL AND COLONIC SEGMENTS INVIVO AND BRUSH-BORDER MEMBRANE-VESICLES INVITRO1989
- Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated CompoundsPharmaceutical Research, 1988
- Comparison of kinetic constants of hexose uptake in four animal species and manComparative Biochemistry and Physiology Part A: Physiology, 1982
- MEASUREMENTS OF INTESTINAL PERMEABILITY USING LOW-MOLECULAR WEIGHT POLYETHYLENE GLYCOLS (PEG-400) .2. APPLICATION TO NORMAL AND ABNORMAL PERMEABILITY STATES IN MAN AND ANIMALS1977
- Absorption, metabolism, and excretion of hydrochlorothiazideClinical Pharmacology & Therapeutics, 1976
- Differential permeability of the proximal and distal rabbit small bowelJournal of Clinical Investigation, 1972
- Absorption, Distribution, Metabolism, and Excretion of Naproxen in Various Laboratory Animals and Human SubjectsJournal of Pharmaceutical Sciences, 1972