Synthesis and Quantitative Structure‐Activity Relationship (QSAR) Analysis of Some Novel Yanthine Oxidase Inhibitors: 6‐(para‐substituted phenyl)‐pteridine‐4‐ones
- 1 January 1985
- journal article
- research article
- Published by Wiley in Quantitative Structure-Activity Relationships
- Vol. 4 (4) , 161-166
- https://doi.org/10.1002/qsar.19850040404
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- The oxidation of 7‐(p‐X‐phenyl)pteridin‐4‐ones (X = Me, H, Br, CN, NO2) with free and immobilized xanthine oxidaseRecueil des Travaux Chimiques des Pays-Bas, 1979
- Pteridine studies: III—13C n.m.r. data of pteridine, some of its derivatives and their covalent σ-adducts with ammonia and waterMagnetic Resonance in Chemistry, 1976
- Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo[1,5-a]pyrimidinesJournal of Medicinal Chemistry, 1976
- Synthesis and biological evaluation of xanthine oxidase inhibitors. Pyrazolo[3,4-d]pyrimidines and pyrazolo[3,4-b]pyridinesJournal of Medicinal Chemistry, 1975
- 3-Hydroxy-1-nitrophenyl-1H-pyrazolo[3,4-b]pyridines as selective inhibitors of rat liver xanthine oxidaseJournal of Medicinal Chemistry, 1974
- Irreversible enzyme inhibitors. CXXII. Nature and dimensions of the hydrophobic bonding region of guanine deaminase and xanthine oxidaseJournal of Medicinal Chemistry, 1968
- Synthese von kristallin‐flüssigen Verbindungen. I. n‐Alkyl‐ und n‐Alkoxyderivate des 3‐Hydroxy‐2,5‐diphenyl‐pyrazinsJournal für Praktische Chemie, 1966
- Effect of allopurinol (4-Hydroxypyrazolo-(3,4-d)pyrimidine) on serum and urinary uric acid in primary and secondary goutThe American Journal of Medicine, 1964
- Recent Developments in the Chemistry of PteridinesAngewandte Chemie International Edition in English, 1964
- The Determination of Enzyme Dissociation ConstantsJournal of the American Chemical Society, 1934