Meal Frequency—A Possible Factor in Human Pathology

Abstract
Epidemiological studies revealed that excessive weight and, in elderly age groups, also hypercholesterolemia, impaired glucose tolerance, and ischemic heart disease was more common among persons with an infrequent meal pattern than among those who customarily ate five or more meals per day. Factors involved in the mechanism of metabolic effects of infrequent feeding are discussed especially with respect to possible pathogenic effects of infrequent feeding in man.