Stabilization of oligonucleotide–polyethylenimine complexes by freeze-drying: physicochemical and biological characterization
- 17 January 2004
- journal article
- Published by Elsevier
- Vol. 95 (1) , 119-131
- https://doi.org/10.1016/j.jconrel.2003.10.021
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Effects of PEGylation on the Preservation of Cationic Lipid/DNA Complexes during Freeze-Thawing and LyophilizationJournal of Pharmaceutical Sciences, 2002
- Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expressionGene Therapy, 2002
- Maintenance of Nonviral Vector Particle Size During the Freezing Step of the Lyophilization Process is Insufficient for Preservation of Activity: Insight From Other Structural IndicatorsJournal of Pharmaceutical Sciences, 2001
- Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesisBiochimica et Biophysica Acta (BBA) - Biomembranes, 2000
- Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agentsGene Therapy, 2000
- Polyethylenimine but Not Cationic Lipid Improves Antisense Activity of 3′-Capped Phosphodiester OligonucleotidesAntisense and Nucleic Acid Drug Development, 1999
- Self-Assembly of Polyamine−Poly(ethylene glycol) Copolymers with Phosphorothioate OligonucleotidesBioconjugate Chemistry, 1998
- Stability of lipid/DNA complexes during agitation and freeze–thawingJournal of Pharmaceutical Sciences, 1998
- Stabilization of gene delivery systems by freeze-dryingInternational Journal of Pharmaceutics, 1997
- DNA Complexes with Polycations for the Delivery of Genetic Material into CellsBioconjugate Chemistry, 1995