A cell line (HBL-100) established from human breast milk
- 1 November 1982
- journal article
- research article
- Published by Springer Nature in Cell and tissue research
- Vol. 227 (3) , 563-568
- https://doi.org/10.1007/bf00204786
Abstract
A continuous cell line (HBL-100) was obtained from primary cultures of cells derived from an early lactation sample of human milk. There was no evidence of a breast lesion in the milk donor. Karyotype analysis showed that all metaphases contained human chromosomes including a large acrocentric marker chromosome. Both desmosomes and cytoplasmic tonofibrils were observed during early passage. HBL-100 cells exhibited several characteristics of transformation including the ability to form colonies in soft agar, an aneuploid chromosome complement, and continuous growth.Keywords
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