Dna Content in Renal Cell Carcinoma: A Comparison between Flow and Static Cytometric Methods

Abstract
Different flow and static cytometric techniques for analysis of DNA content were compared using imprints, fresh and paraffin-embedded tissues from renal cell carcinomas. All methods discriminated between diploid-hear diploid and aneuploid samples and gave comparable results concerning modal ploidy levels (r=0.744-0.970). For retrospective investigations of renal cell carcinoma, flow cytometry using paraffin-embedded tissues seemed to be the method of choice in determination of DNA content.