Pulmonary Changes in Malignant Trophoblastic Disease

Abstract
The findings in the chest radiographs of 66 patients suffering from malignant trophoblastic disease are reviewed. Pulmonary changes are due to embolic phenomena which may cause secondary deposits, pulmonary infarction, and cor pulmonale. Metastases may be simple or multiple, discrete or ill-defined, evolving or regressing. In young women of child-bearing age the possibility of M.T.D. should be considered in the interpretation of unusual chest radiographs. Cases of acute pulmonary hypertension are described in this series; none of these patients developed chronic pulmonary hypertension. Diagnostic curettage is dangerous and is to be avoided.

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