Nucleotide sequence of tworasHrelated-genes isolated from the yeastSaccharomyces cerevisiae
- 25 April 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 12 (8) , 3611-3618
- https://doi.org/10.1093/nar/12.8.3611
Abstract
A complete nucleotide sequence of two ras -related yeast genes (c- rasSC-1 and c- rasSC-2 ) isolated from the yeast strain Saccharomyces cerevisiae is reported. They encode predicted polypeptides of 40,000 and 41,000 daltons, respectively. The N-terminal 170 amino acids from both genes show extensive amino acid homology to other ras genes from vertebrates, whereas their C-termini have diverged. These genes should be useful in the elucidation of a normal biological function of ras-related genes in a simple system like yeast.Keywords
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