LABORATORY MONITORING OF HEPARIN-THERAPY - THE EFFECT OF DIFFERENT SALTS OF HEPARIN ON THE ACTIVATED PARTIAL THROMBOPLASTIN TIME - AN ANALYSIS OF THE 1978 AND 1979 CAP HEMATOLOGY SURVEY
- 1 January 1980
- journal article
- research article
- Vol. 74 (4) , 569-574
Abstract
Data from the 1978 CAP [College of American Pathologists] Hematology Survey were analyzed for the effect of Na and Ca salts of heparin on the activated partial thromboplastin time (APTT). The Na salt of heparin prolongs the APTT more than the Ca salt at a heparin concentration of 0.2 U/ml. There was a variable response of the different APTT reagents to the different heparin salts. Data from the 1979 CAP Hematology Survey showed a greater sensitivity of the Automated APTT reagent and the Platelin Plus Activator of General Diagnostics compared with Actin (Dade) and Thrombofax (Ortho) at therapeutic heparin levels of 0.2-0.4 U/ml. The 1979 CAP heparin questionnaire results are presented and analyzed.This publication has 4 references indexed in Scilit:
- EFFECT OF HEPARIN ON ACTIVATED PARTIAL THROMBOPLASTIN TIME1978
- Anticoagulant activities of lung and mucous heparinsThrombosis Research, 1978
- Variation among Commercial Activated Partial Thromboplastin Time Reagents in Response to HeparinAmerican Journal of Clinical Pathology, 1977
- ACTIVATED PARTIAL THROMBOPLASTIN TIME AS A MONITOR OF HEPARIN THERAPY - WARNING1977