Carbon-13 nuclear magnetic resonance assignments and biosynthesis of versicolorin A in Aspergillus parasiticus

Abstract
The 13C n.m.r. spectrum of versicolorin A has been assingned. The distributions of 13C label and of the intact acetate units have been determined from the 13C n.m.r. spectra of versicolorin A derived from singly and doubly labelled [13C]acetate. The biosynthesis of versicolorin A in relation to that of previously determined C20 anthraquinones and aflatoxin B1 is discussed. The absolute configuration of versicolorin A is deduced.