NEUROPSYCHIATRIC LUPUS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 7  (3) , 325-333
Abstract
Systemic lupus erythematosus (SLE) patients (66) followed prospectively had 77 episodes of neuropsychiatric lupus (NPL). Patients with NPL had more SLE manifestations than patients without NPL. Serologic data and CSF analysis were not helpful in identifying an episode of NPL. EEG was abnormal in more than 1/2 and brain scans in more than 3/4 of patients. In 74 episodes with a known outcome, 54 improved, 44 having been treated with increased corticosteroids. Patients with NPL had a higher incidence of deaths compared to patients without NPL.