Cardiac Functional Analysis with Multi–Detector Row CT and Segmental Reconstruction Algorithm: Comparison with Echocardiography, SPECT, and MR Imaging

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Abstract
PURPOSE: To evaluate accuracy of cardiac functional analysis with multi–detector row computed tomography (CT) and segmental reconstruction algorithm over a range of heart rates. MATERIALS AND METHODS: Institutional review board approval was obtained. Informed consent was not required. Multi–detector row CT (500-msec rotation time, 8 × 1-mm detector collimation) and magnetic resonance (MR) imaging were performed in 50 patients (28 men, 22 women; age range, 46–84 years; mean age, 67 years). Two-dimensional echocardiography was performed in 41 patients, and electrocardiographically (ECG)-gated single photon emission computed tomography (SPECT) was performed in 27. End-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), and left ventricular (LV) mass were estimated with multi–detector row CT and compared with values estimated with MR imaging, which served as the reference standard. Additionally, EF values estimated with multi–detector row CT, echocardiography, and SPECT were compared wi...