LYNESTRENOL, AN AMPLIFIER OF LYMPHOCYTE STIMULATION

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 27  (1) , 16-19
Abstract
Lynestrenol, a synthetic steroid progesterone-like substance, enhances the stimulation of normal human lymphocytes. It increases the phytohemagglutinin response and the mixed-lymphocyte cultures. This augmentation can, in some cases, be > 100% of the phytohemagglutinin or mixed lymphocyte reaction baseline. There is no significant effect on the pokeweed mitogen stimulation. It is concluded that lynestrenol can modulate, in vitro, some T [thymus-derived] cell functions.

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