Drug Malabsorption and Resistant Tuberculosis in HIV-Infected Patients
- 2 February 1995
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 332 (5) , 336-337
- https://doi.org/10.1056/nejm199502023320518
Abstract
Directly observed therapy for tuberculosis has been advocated as a way to improve compliance and control the emergence of drug resistance.1,2 We recently cared for two patients with human immunodeficiency virus (HIV) infection who were receiving therapy under direct observation when they relapsed with drug-resistant isolates of Mycobacterium tuberculosis, presumably due to subtherapeutic drug levels caused by malabsorption.Keywords
This publication has 3 references indexed in Scilit:
- The Effect of Directly Observed Therapy on the Rates of Drug Resistance and Relapse in TuberculosisNew England Journal of Medicine, 1994
- Malabsorption of Antimycobacterial MedicationsNew England Journal of Medicine, 1993
- Malabsorption of Antituberculosis Medications by a Patient with AIDSNew England Journal of Medicine, 1992