Biosensors for glycaemic control
- 1 December 2001
- journal article
- research article
- Published by Emerald Publishing in Sensor Review
- Vol. 21 (4) , 297-304
- https://doi.org/10.1108/02602280110406954
Abstract
To overcome the problem of metabolic crashes as hypoglycaemic as well as hyperglycaemic episodes in diabetic patients the continuous or at least very frequent checking of the circulating intracorporal glucose concentration is necessary. Biosensors measuring glucose in vivo are suitable for estimating the transient interstitial glucose concentration in human beings. Biologically and/or biochemically caused processes are responsible for limiting the functional stability of implanted sensors. It is now possible to advance beyond the current practice of hand making glucose sensors in the laboratory and produce these sensors as industrial products with reproducible characteristics. This gives us a real chance to avoid hypoglycaemic and hyperglycaemic metabolic attacks.Keywords
This publication has 9 references indexed in Scilit:
- Stability of immobilized enzymes as biosensors for continuous application in vitro and in vivoJournal of Molecular Catalysis B: Enzymatic, 1999
- Influence of polymerization parameters and entrapment in poly(hydroxyethyl methacrylate) on activity and stability of GODJournal of Molecular Catalysis B: Enzymatic, 1999
- Subpicosecond-pulse laser microstructuring for enhanced reproducibility of biosensorsSensors and Actuators B: Chemical, 1997
- Integrated implantable device for long-term glucose monitoringBiosensors and Bioelectronics, 1995
- Continuous in vivo monitoring in diabetes: the subcutaneous glucose concentrationActa Anaesthesiologica Scandinavica, 1995
- Clinical Usefulness of the Glucose Concentration in the Subcutaneous Tissue - Properties and Pitfalls of Electrochemical BiosensorsHormone and Metabolic Research, 1994
- Calibration in dogs of a subcutaneous miniaturized glucose sensor using a glucose meter for blood glucose determinationBiosensors and Bioelectronics, 1992
- Design and in vitro studies of a needle-type glucose sensor for subcutaneous monitoringAnalytical Chemistry, 1991
- Needle enzyme electrodes for biological studiesBiosensors, 1986