Linkage Studies between HL-A and GPT Polymorphisms and Other Genetic Markers
- 1 January 1976
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 30 (1) , 68-73
- https://doi.org/10.1111/j.1423-0410.1976.tb04835.x
Abstract
The phenotypes of 56 families with 126 children from the Hamburg area as well as gene frequencies and segregation of the genetic markers GPT, AP, ADA, AK, PGM1, PGM3, 6-PGD, CHE, C3, Gc, Tf, Hp and Cp were studied. In regard to linkage, the informative families were correlated to the results of HL-A and GPT typing. The linkage was tested according to the sequential test by MORTON (1955). See article. For other gene loci, linkage to the HL-A or GPT system could not be proved. But the positive lod scores of HL-A/GPT, HL-A/AP and GPT/6-PGD may give indication for linkage.Keywords
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