Topographical and Temporal Diversity of the Human Skin Microbiome
Top Cited Papers
- 29 May 2009
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 324 (5931) , 1190-1192
- https://doi.org/10.1126/science.1171700
Abstract
The Close and Personal Biome: Fortunately, our skin is readily accessible for ecological studies of the microbial communities that influence health and disease states. Grice et al. (p. 1190 ) present a metagenomic survey of body sites from 10 healthy human individuals sampled over time. Although, altogether 18 phyla were discovered, only a few predominated. The most diverse communities were found on the forearm and the least behind the ear, but between people the microorganisms living behind the knees, in the elbow, and behind the ear were most similar. This finding might have some bearing on the common occurrence of atopic dermatitis in these zones, although no similar relationship was discerned between skin microbial flora and psoriasis.Keywords
This publication has 10 references indexed in Scilit:
- Matriptase-Deficient Mice Exhibit Ichthyotic Skin with a Selective Shift in Skin MicrobiotaJournal of Investigative Dermatology, 2009
- The influence of sex, handedness, and washing on the diversity of hand surface bacteriaProceedings of the National Academy of Sciences, 2008
- Substantial Alterations of the Cutaneous Bacterial Biota in Psoriatic LesionsPLOS ONE, 2008
- A diversity profile of the human skin microbiotaGenome Research, 2008
- Molecular analysis of human forearm superficial skin bacterial biotaProceedings of the National Academy of Sciences, 2007
- The ribosomal database project (RDP-II): introducing myRDP space and quality controlled public dataNucleic Acids Research, 2006
- Epidermal barrier formation and recovery in skin disordersJournal of Clinical Investigation, 2006
- Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureusThe Lancet, 2006
- PsoriasisNew England Journal of Medicine, 2005
- Introducing DOTUR, a Computer Program for Defining Operational Taxonomic Units and Estimating Species RichnessApplied and Environmental Microbiology, 2005