Selective O-benzoylation in aminoglycoside antibiotics.
- 1 January 1977
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 25 (8) , 2089-2097
- https://doi.org/10.1248/cpb.25.2089
Abstract
The 3''- and 4''-hydroxy groups of N-protected butirosin or kanamycin derivatives resist benzoylation in an aqueous medium, furnishing an effective method for chemical modifications of these antibiotics.This publication has 2 references indexed in Scilit:
- Synthesis of aminotrideoxybutirosin A, a chemically modified antibiotic active against butirosin-resistant bacteria.The Journal of Antibiotics, 1975
- 5"-Amino-3',4',5"-trideoxybutirosin A, a new semisynthetic aminoglycoside antibiotic.The Journal of Antibiotics, 1975