EFFECT OF ESTERS OF PARAHYDROXYBENZOIC ACID ON CANDIDA AND YEAST-LIKE FUNGI

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Abstract
The development of Candida albicans infection, or moniliasis, following antibiotic therapy has received considerable attention recently. The true incidence of this condition, however, is debatable. Lipnik, Kligman, and Strauss1 have reviewed the subject in an attempt to define the possible role that C. albicans may play in the production of side reactions to antibiotics. They concluded that true moniliasis is very rare in people treated with antibiotics and that the mere presence of the organism in the oral cavity or in the gastrointestinal tract does not justify a diagnosis of C. albicans infection. Having treated hundreds of patients with wide-spectrum antibiotics in this clinic we are of the same opinion. Our evidence suggests that yeast-like organisms may be found in varying numbers in the intestinal tract as part of its normal flora (presumably true for the oral flora, too) in a large percentage of untreated persons, provided adequate isolation