Cerebral Hemodynamic and Metabolic Studies in Patients with Congestive Heart Failure

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Abstract
Cerebral blood flow and metabolism has been studied in subjects with congestive heart failure; a modification of the N2O technique of Kety and Schmidt was employed. The patients were categorized as to the severity of the congestive state according to clinical criteria. In subjects with mild to moderate congestive failure the cerebral vascular resistance was increased but cerebral perfusion was normal. On the other hand, in patients with severe congestive failure there was a significant reduction in cerebral blood flow. Cerebral metabolism was not affected by the congestive state. Relief of the congestive heart failure was associated with a reduction in cerebral blood flow.

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