Chronic manganese oxide administration to preweanling rats: Manganese accumulation and distribution
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 6 (1) , 217-226
- https://doi.org/10.1080/15287398009529844
Abstract
Mn accumulation was evaluated in selected tissues of preweanling rats dosed daily with particulate Mn3O4. Significant findings include a high rate of Mn accumulation in the preweanling rat; a Mn dose-related acceleration of postpartum liver Fe depletion; a Mn dose-related depression in red blood cells, hematocrit, Hb, body weight, and survival by 21 day postpartum; and a Mn distribution in tissues with liver > brain .gtoreq. kidney > testes at 18-21 day of age. Environmental implications are discussed.This publication has 15 references indexed in Scilit:
- Intestinal absorption of particulate matterLife Sciences, 1977
- Influence of age and milk diet on cadmium absorption from the gutToxicology and Applied Pharmacology, 1977
- The blood-brain barrierExperimental Eye Research, 1977
- Effect of Age on Gastrointestinal Absorption (Fe, Sr, Pb) in the RatJournal of Nutrition, 1972
- Postnatal Development of the Small Intestine of the Rat: Changes in Mucosal Morphology at WeaningPediatric Research, 1969
- Tissue concentrations of manganese and adrenal functionAmerican Journal of Physiology-Legacy Content, 1966
- Dependence of manganese turnover on intakeAmerican Journal of Physiology-Legacy Content, 1966
- Intestinal Invertase: Precocious Development of Activity after Injection of HydrocortisoneScience, 1964
- The Ingestion of Proteins and Colloidal Materials by Columnar Absorptive Cells of the Small Intestine in Suckling Rats and MiceThe Journal of cell biology, 1959
- Extension of Multiple Range Tests to Group Means with Unequal Numbers of ReplicationsPublished by JSTOR ,1956