Metabolism of 2(RS),3‐epiminosqualene to 24(RS),25‐epiminolanosterol byGibberella fujikuroi
- 1 April 1988
- Vol. 23 (4) , 375-376
- https://doi.org/10.1007/bf02537354
Abstract
The metabolic fate of 2(RS),3-epiminosqualene (Isq.), a demonstrable inhibitor of the 2,3-oxidosqualene-lanosterol cyclase, has been studied inGibberella fujikuroi. The fungus transforms Isq. to a tetracyclic product for which the 24(RS),25-epiminolanosterol (EL) formulation was indicated by chromatographic and spectral data. The results are consistent with the pathway: Isq.→2,3-imino-22, 23-oxidosqualene→EL.This publication has 13 references indexed in Scilit:
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