Recurrent Hematuria in Childhood

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Abstract
Recurrent hematuria, unaccompanied by obvious renal disease or urinary-tract lesions, was associated with microscopic glomerular disease in 21 of 31 patients. On bright-field microscopy, segmental glomerulitis was the most common lesion. In 11 cases electron-dense deposits in the basement membrane of glomerular capillaries were similar to those in resolving acute glomerulonephritis. Some of the clinical data, including glomerulonephritis in family members and a preponderance of males, also suggested a relation between recurrent hematuria and glomerulonephritis. None of the patients had abnormal renal function within seven years of the onset of hematuria. It is possible that these patients are in a latent phase preceding chronic glomerulonephritis.

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