EXPERIMENTAL INVESTIGATION OF POSTSTENOTIC DILATATION IN ISOLATED ARTERIES
- 1 January 1964
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 42 (1) , 53-63
- https://doi.org/10.1139/y64-007
Abstract
Isolated human and dog iliac arteries were mounted in a double-chambered plethysmograph and perfused with merthiolate solution. Various degrees of stenosis were produced by plastic rings. Only arteries with moderate stenoses (i.e. those that produced a distal thrill and bruit) developed poststenotic dilatation, but all of them did. The dilatation usually started within 5 minutes, progressed rapidly for 20 to 30 minutes, and then more slowly for up to 3 days. Pressure–volume measurements showed that the dilated segment was more distensible than normal.Keywords
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