Amino acids with anabolic properties
- 1 May 1998
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Clinical Nutrition and Metabolic Care
- Vol. 1 (3) , 263-272
- https://doi.org/10.1097/00075197-199805000-00005
Abstract
Experimental studies have clearly demonstrated both the indispensability in stress situations of amino acids, previously considered to be non-essential, and the importance of the specific properties of these same amino acids. Glutamine, arginine and their precursors/metabolites, ornithine and α-ketoglutarate, exert anabolic or anticatabolic effects through their involvement in protein metabolism, in the immune response and in cell proliferation. Clinical studies suggest that the supplementation of nutritional therapy with these amino acids can be of significant benefit for injured patients.Keywords
This publication has 96 references indexed in Scilit:
- Ornithine alpha-ketoglutarate counteracts thymus involution and glutamine depletion in endotoxemic ratsClinical Nutrition, 1996
- Effect of Parenteral ?-Glutamine on Muscle in the Very Severely I11Nutrition, 1996
- The effects of a new amino-acid dipeptide solution on nitrogen balance and humoral growth factors in the postoperative state in manClinical Nutrition, 1995
- Functional and Metabolic Changes in Intestinal Mucosa of Rats After Enteral Administration of Ornithine α‐Ketoglutarate SaltJournal of Parenteral and Enteral Nutrition, 1995
- Metabolism of ornithine, α-ketoglutarate and arginine in isolated perfused rat liverBritish Journal of Nutrition, 1995
- Effect of Glutamine‐Supplemented Total Parenteral Nutrition on Recovery of the Small Intestine After Starvation AtrophyJournal of Parenteral and Enteral Nutrition, 1993
- The long-term effect of postoperative TPN supplemented with glycyl-glutamine on protein synthesis in skeletal muscleClinical Nutrition, 1991
- Influence of glutamine and branched chain amino acids on the jejunal atrophy associated with parenteral nutritionJournal of Gastroenterology and Hepatology, 1991
- Effects of an amino acid solution enriched with either branched chain amino acids or ornithine-α-ketoglutarate on the postoperative intracellular amino acid concentration of skeletal muscleBritish Journal of Surgery, 1990
- Nitrogen sparing effect of ornicetil® in the immediate postoperative state clinical biochemistry and nitrogen balanceClinical Nutrition, 1985