Anti-mutagenic and immuno-stimulatory properties of lactic acid bacteria
- 1 May 1995
- journal article
- Published by Springer Nature in World Journal of Microbiology and Biotechnology
- Vol. 11 (3) , 294-298
- https://doi.org/10.1007/bf00367102
Abstract
Statistically significant antigenotoxic activity was exerted by six of nine strains of lactic acid bacteria tested (Lactobacillus delbrueckii subsp. bulgaricus, Staphylococcus carnosus, Streptococcus thermophilus, L. rhamnosus, Enterococcus faecium and En. faecalis) against nitrovin and 2-aminofluorene in Salmonella typhimurium TA100 and TA97. The mutagenic activity of both mutagens was substantially decreased by viable bacteria; cells heated to 100°C for 15 min were ineffective. In vitro, En. faecium stimulated the basic metabolic activities of human neutrophils which were essential for their antimicrobial and cytotoxic activity, whereas stimulation of guinea-pig macrophages was not so effective. Similar immuno-stimulatory effects were observed with both viable and heat-inactivated bacteria.Keywords
This publication has 24 references indexed in Scilit:
- Potential of using lactic acid bacteria for therapy and immunomodulation in manFEMS Microbiology Reviews, 1993
- The possible role of probiotics as dietary antimutagensMutation Research Letters, 1991
- The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.Journal of Clinical Investigation, 1989
- Probiotics in man and animalsJournal of Applied Bacteriology, 1989
- SUCCESSFUL TREATMENT OF RELAPSING CLOSTRIDIUM DIFFICILE COLITIS WITH LACTOBACILLUS GGPublished by Elsevier ,1987
- Antimicrobial substance from a human Lactobacillus strainAntimicrobial Agents and Chemotherapy, 1987
- Molecular basis of activation and regulation of the phagocyte respiratory burst.Annals of the Rheumatic Diseases, 1987
- Indigenous bacteria that influence the number of Salmonella typhimurium in the spleen of intravenously challenged miceCanadian Journal of Microbiology, 1980
- A factor in yogurt which lowers cholesteremia in manAtherosclerosis, 1977
- Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity testMutation Research/Environmental Mutagenesis and Related Subjects, 1975