THE FUNCTIONAL CAPACITY OF THE KIDNEY DENERVATED BY AUTOTRANSPLANTATION IN THE DOG1
Open Access
- 1 February 1958
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 37 (2) , 185-193
- https://doi.org/10.1172/jci103597
Abstract
Results from separate but simultaneous studies on the 2 kidneys of 6 dogs having one kidney autotransplanted into the iliac fossa and the opposite kidney intact are presented. The autotransplanted kidney demonstrated no persistent functional defects. Complete denervation occurring during the trans- plantation procedure did not result in any consistent abnormality in the tubular transport of NaCl. Responses of conventionally denervated kidneys did not differ in any major respect from the autotransplanted kidneys. Conventional denervation, as employed in other studies, thus appears to be a satisfactory means of depriving the kidney of its nerve supply.Keywords
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