SERUM BILE-ACIDS IN ACUTE HEPATITIS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 16  (1) , 145-149
Abstract
Serum concentrations of cholic (CCA) and chenodeoxycholic (CCDA) acid were measured by radioimmunoassay in 27 patients with acute hepatitis of various etiologies. In the icteric phase, serum bile acids were strongly elevated, usually with a predominance of CCA. As the disease resolved, CCDA was the predominant bile acid in serum in most patients. Serum CCA and CCDA levels returned to normal values at approximately the same time as aminotransferases. Determinations of serum bile acids evidently provide no further information than conventional liver tests during the course of acute hepatitis.