HIGH MONOAMINE OXIDASE ACTIVITY IN THE TICK BOOPHZLUS MICROPLUS, AND INHIBITION BY CHLORDIMEFORM AND RELATED PESTICIDES.
- 1 September 1974
- journal article
- Published by Wiley in Australian Journal of Entomology
- Vol. 13 (3) , 207-210
- https://doi.org/10.1111/j.1440-6055.1974.tb02174.x
Abstract
Homogenates of the tick, Boophilus microplus (Canestrini), contain high levels of monoamine oxidase (MAO), far in excess of those hitherto found in insects and comparable to those found in rat liver. The enzyme has been demonstrated in a diversity of organs including the synganglion, peripheral nerves and salivary glands. The enzyme is inhibited by pargyline and tranylcypromine, as well as chlor‐dimeform [N′‐(4‐chloro‐o‐tolyl)‐N, N‐dimethyl formamidine] and several related formamidine acaricides. Results point, if only circumstantially, to some involvement of MAO inhibition in the action of formamidines on B. microplus. However MAO inhibition is considered unlikely to be the sole mechanism in formamidine poisoning.Keywords
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