SEXUAL PRECOCITY IN A 5-YEAR-OLD BOY WITH INTERSTITIAL-CELL TUMOR OF THE TESTIS

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Abstract
THERE have been previously recorded only 9 cases of sexual precocity due to the hormonal effects of an interstitial-cell tumor of the testis. The pertinent literature has been reviewed by Cook et at. (1). The following case is reported in order to aid in the characterization of the clinical and endocrinologic features of this unusual syndrome. N. R., a white male child, was first seen at the age of 5 years on September 4, 1950. He had been born on June 7, 1945. He was the product of a first pregnancy and weighed 6 pounds 15 ounces, and measured 2½ inches in length at birth. Early pediatric development was not remarkable. In 1949 during his fourth year, his general body growth was noted to be rapid and in January 1950 the mother noted a few pubic hairs developing. Since that time until September 1950 when he was first admitted to our clinic, there was progressive and rapid genital development, frequent acneform eruption about the face and shoulders, and a marked change in his voice. His health had otherwise been good, except for recurrent tonsillitis necessitating a tonsillectomy in May 1950.

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