INTERSTITIAL CELL TUMOR OF THE TESTIS. STUDY OF A 5-YEAR-OLD BOY WITH PSEUDO-PRECOCIOUS PUBERTY*
- 1 June 1952
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 12 (6) , 725-734
- https://doi.org/10.1210/jcem-12-6-725
Abstract
A 9th case of interstitial cell tumor associated with pseudo-precocious puberty in a child is reported, along with a pathologic descr. of the tumor and postoperative follow-up data. Chromatographic studies of the excessive urinary output of 17-ketosteroids showed that these were predominantly 3-a-OH-17-ketosteroids. Removal of this benign tumor resulted in cessation of the abnormal andro-genic activity. This type of tumor in children appears to be limited to the period between 2 and 6 yrs. of age, and the clinical picture seems to be uniform.Keywords
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