COMPARISON OF METHODS FOR ASSESSING THE ANTIGENIC RESPONSE TO PERTUSSIS VACCINE
- 1 April 1956
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 2 (2) , 94-101
- https://doi.org/10.1139/m56-014
Abstract
Five methods which might be used for measuring the effectiveness of pertussis vaccines were compared using three vaccines. The methods did not yield the same relative results. It is highly probable that a mechanism other than humoral antibodies plays an important part in the mouse protection test since by this test the vaccines were graded differently than by a test depending on passive protection.Keywords
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- HISTAMINE SHOCK IN MICE SENSITIZED WITH HEMOPHILUS PERTUSSIS VACCINE1948