A CASE OF FEMINIZING ADRENAL TUMOR IN A GIRL

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Abstract
A case of feminizing adrenal tumor presenting as isosexual precocity in a girl 5½ years of age is described. Urinary 17-ketosteroids, estrogens, 17-hydroxysteroids and pregnanetriol were determined both before and after surgical removal of the tumor; after operation the only difference observed on the chromatograms was the absence of dehydroepiandrosterone. The excretion of 17-ketosteroids and estrogens, though within the adult range, was abnormally high for a child of this age. This high excretion was probably due to the presence of the tumor.