INFLUENZA A PRIME: A CLINICAL STUDY OF AN EPIDEMIC CAUSED BY A NEW STRAIN OF VIRUS

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Abstract
A comprehensive clinical and bacteriological study was made of 367 patients admitted during an epidemic caused by a new antigenic variant of influenza A virus which infected soldiers of an army installation in Feb. 1947. In defining the symptomatology of the disease, data from 76 patients admitted during the epidemic peak were used. Infection with the new virus (influenza A prime) produced an acute, benign, febrile disease of abrupt onset characterized by moderate prostration, headache, myalgia, coryza, and dry cough, thus not differing materially from previously described influenza. Of special interest was the immediate increase in carriers of beta hemolytic streptococci observed subsequent to the peak of the influenza epidemic, culminating in a frank epidemic of streptococcal pharyngitis the following month.

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