Transplantation of Rat Bone Marrow in Irradiated Mice: Effect of Exposure Rate
- 30 October 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 146 (3644) , 663-664
- https://doi.org/10.1126/science.146.3644.663
Abstract
Mice were irradiated at several different exposure rates so that they received a total of 900 roentgens over the whole body. Within 2 hours they were injected with rat bone marrow. The success of the transplantation depended upon the rate at which the animals had been irradiated: the higher the rate, the greater the success of the grafts. Failure of grafts in mice subjected to low exposure-rates was associated with antibody formation. The data indicate existence of an immune mechanism which is dependent on the radiation exposure-rate.Keywords
This publication has 5 references indexed in Scilit:
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- Measurements in a total-body irradiation facilityThe International Journal of Applied Radiation and Isotopes, 1961
- Analysis of Serum from Lethally Irradiated Mice Treated with Rat Bone MarrowThe Journal of Immunology, 1959
- ALKALINE PHOSPHATASE OF CELL NUCLEI1951