Design, Synthesis, and In Vivo Efficacy of Glycine Transporter‐1 (GlyT1) Inhibitors Derived from a Series of [4‐Phenyl‐1‐(propylsulfonyl)piperidin‐4‐yl]methyl Benzamides
- 3 August 2006
- journal article
- research article
- Published by Wiley in ChemMedChem
- Vol. 1 (8) , 807-811
- https://doi.org/10.1002/cmdc.200600097
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Discovery of N-(2-aryl-cyclohexyl) substituted spiropiperidines as a novel class of GlyT1 inhibitorsBioorganic & Medicinal Chemistry Letters, 2006
- Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profileBioorganic & Medicinal Chemistry Letters, 2006
- Novel inhibitors of the type 1 transporter for glycine (GlyT1) as antipsychotic agentsExpert Opinion on Therapeutic Patents, 2005
- Neurochemical, Electrophysiological and Pharmacological Profiles of the Selective Inhibitor of the Glycine Transporter-1 SSR504734, a Potential New Type of AntipsychoticNeuropsychopharmacology, 2005
- Recent progress in the use of glycine transporter-1 inhibitors for the treatment of central and peripheral nervous system diseasesExpert Opinion on Therapeutic Patents, 2004
- Development of a Custom High-Throughput Preparative Liquid Chromatography/Mass Spectrometer Platform for the Preparative Purification and Analytical Analysis of Compound LibrariesJournal of Combinatorial Chemistry, 2003
- N[3‐(4′‐fluorophenyl)‐3‐(4′‐phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transportBritish Journal of Pharmacology, 2001
- Schizophrenia: the fundamental questionsBrain Research Reviews, 2000
- Antipsychotic drug doses and neuroleptic/dopamine receptorsNature, 1976
- Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse BrainActa Pharmacologica et Toxicologica, 1963