The structure of the Escherichia coli EF-Tu· EF-Ts complex at 2.5 Å resolution
- 8 February 1996
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 379 (6565) , 511-518
- https://doi.org/10.1038/379511a0
Abstract
The crystal structure of the EF-Tu·EF-Ts complex from Escherichia coli has been determined to a resolution of 2.5 Å. The complex contains two subunits of each of the elongation factors. The two EF-Ts molecules form a tight dirtier, but there is little contact between the two EF-Tu molecules. The interaction of EF-Ts with EF-Tu results principally in the disruption of the Mg2+ ion binding site, thereby reducing the affinity of EF-Tu for guanine nucleotides.Keywords
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