On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella typhimurium and BX1 from Maize, Two Evolutionarily Related Enzymes
- 23 September 2005
- journal article
- research article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 352 (3) , 608-620
- https://doi.org/10.1016/j.jmb.2005.07.014
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan SynthaseJournal of Molecular Biology, 2002
- Cryo-crystallography of a True Substrate, Indole-3-glycerol Phosphate, Bound to a Mutant (αD60N) Tryptophan Synthase α2β2 Complex Reveals the Correct Orientation of Active Site αGlu49Journal of Biological Chemistry, 1998
- Crystal Structures of a Mutant (βK87T) Tryptophan Synthase α2β2 Complex with Ligands Bound to the Active Sites of the α- and β-Subunits Reveal Ligand-Induced Conformational ChangesBiochemistry, 1997
- Characterization of the functional role of a flexible loop in the .alpha.-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesisBiochemistry, 1993
- Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complexBiochemistry, 1992
- The tryptophan synthase bienzyme complex transfers indole between the .alpha.- and .beta.-sites via a 25-30 .ANG. long tunnelBiochemistry, 1990
- Calorimetric study of tryptophan synthase α‐subunit and two mutant proteinsInternational Journal of Peptide and Protein Research, 1982
- pH dependence of stability of the wild-type tryptophan synthase α-subunit and two mutant proteins (Glu49 → Met or Gln)Journal of Molecular Biology, 1980
- Tryptophan Synthase: Structure, Function, and Subunit InteractionPublished by Wiley ,1979
- Atomic coordinates for triose phosphate isomerase from chicken muscleBiochemical and Biophysical Research Communications, 1976