Jaundice Following the Administration of 50 mg. of Chlorpromazine
- 22 September 1955
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 253 (12) , 499-502
- https://doi.org/10.1056/nejm195509222531203
Abstract
CURRENT interest in chlorpromazine — 10 (ydimethylaminopropyl) -2-chlorophenothiazine —hydrochloride is reflected in the widespread use of this drug in many of the specialties of medicine. First introduced by French workers,1 , 2 it has been used for the suppression of nausea and vomiting of varied origin.3 4 5 More recently, it has been recommended for the treatment of mental disturbances6 , 7 and intractable hiccup.8 The known side effects are drowsiness, postural hypotension,9 which may lead to renal insufficiency, tachycardia, dryness of the mouth, nasal congestion, pyrosis and constipation. Miosis and sometimes mydriasis, mild increase in temperature, agranulocytosis,10 11 12 eosinophilia13 and allergic reactions, which are for the . . .Keywords
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