Fluoridated Water and the Skeletal Uptake of Sr85 and Ca45 by Young Rats

Abstract
This investigation dealt with the effect of various levels of fluoride in the drinking water upon the accumulation of Sr85 and Ca45 in the skeleton of young rats. The results showed that fluoride at 1 ppm in the water had no effect upon the retention of Sr85 and Ca45 in the skeleton of the rats. A level of 100 ppm F- in the water, which increased the total fluoride intake by a factor of about 10, would be expected to increase the bone concentration of ingested radiostrontium by about 30% in rats under the conditions of this study.