Thermal stability of foot-and-mouth disease virus
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 70 (1) , 21-32
- https://doi.org/10.1007/bf01320790
Abstract
The thermal stabilities of 146S component of seven strains of foot-and-mouth disease virus were found to differ considerably. Inactivation of infectivity with acetylethyleneimine (AEI) reduced the thermal stabilities of all but one of the viruses. Treatment of AEI inactivated and control virus preparations with glutaraldehyde stabilized 146S particles to a considerable extent, whereas treatment with dimethyl suberimidate was less effective. In similar experiments with 75S, natural empty particles, the thermal stabilities were lower than those of the corresponding 146S particles. Treatment of 75S particles with AEI appeared to have no direct effect on the protein-protein interactions involved in 75S capsid integrity. As with 146S particles, glutaraldehyde stabilized 75S particles.This publication has 16 references indexed in Scilit:
- ON THE STABILITY OF BOVINE FOOT-AND-MOUTH DISEASE VIRUS DEPENDENT ON pH.Acta Pathologica Microbiologica Scandinavica, 2009
- Microcentrifuge desalting: A rapid, quantitative method for desalting small amounts of proteinAnalytical Biochemistry, 1980
- Chemical Cross-Linking: Reagents and Problems in Studies of Membrane StructureAnnual Review of Biochemistry, 1977
- The effect of acetylethyleneimine upon a strain of inactivated foot-and-mouth disease virus stored at 4° CArchiv für die gesamte Virusforschung, 1975
- A Comparative Chemical and Serological Study of the Full and Empty Particles of Foot-and Mouth Disease VirusJournal of General Virology, 1975
- Stabilizing the immunizing antigen of foot-and-mouth disease virus by fixation with formaldehydeArchiv für die gesamte Virusforschung, 1972
- Nature of the Inactivating Action of Trypsin on Foot-and-Mouth Disease VirusJournal of General Virology, 1967
- CHEMICAL + PHYSICAL PROPERTIES OF VIRTUALLY PURE FOOT-+-MOUTH DISEASE VIRUS1964
- In vitromeasurement of the potency of inactivated foot-and-mouth disease virus vaccinesEpidemiology and Infection, 1963
- Dissociation of Foot-and-Mouth Disease Virus into its Nucleic Acid and Protein ComponentsNature, 1961