The N-Terminal Transactivation Domain Confers Target Gene Specificity of Hypoxia-inducible Factors HIF-1α and HIF-2α
- 1 November 2007
- journal article
- Published by American Society for Cell Biology (ASCB) in Molecular Biology of the Cell
- Vol. 18 (11) , 4528-4542
- https://doi.org/10.1091/mbc.e06-05-0419
Abstract
The basic helix-loop-helix-Per-ARNT-Sim–proteins hypoxia-inducible factor (HIF)-1α and HIF-2α are the principal regulators of the hypoxic transcriptional response. Although highly related, they can...Keywords
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