Über die Cholesterinesterasen und ihre Beziehungen zur Fettresorption und zum Fetttransport

Publisher Website
Google Scholar
Abstract
Dry powders obtained by the same procedure from hog pancreas and from hog liver were tested for their capacity to hydrolyze fatty acid esters of cholesterol and to synthesize such esters from their components. The pancreatic enzyme effected esterification most rapidly at pH = 5.3. At this pH esterification was about 15 times as fast as hydrolysis. The rate at which esters were hydrolyzed was practically independent of the pH (5.3-8.0). Ester formation, but not ester hydrolysis proceeded only in the presence of glycocholic acid. The liver prep. effected no ester formation at all, but catalyzed ester hydrolysis at a somewhat higher rate than the pancreatic esterase. The roles of the pancreatic enzyme and of bile acids for fat absorption and of the liver enzyme for fat transport were discussed.

This publication has 6 references indexed in Scilit: