Inhibition of Human Immunodeficiency Virus (HIV) Production by 5′-Hydrogenphosphonates of 3′-Azido-2′,3′- dideoxynucleosides
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 10 (1-3) , 351-354
- https://doi.org/10.1080/07328319108046477
Abstract
3′-Azido-2′.3′-dideoxynucleoside 5′-hydrogenphos-phonates with thymine, adenine, guanine and cytosine bases inhibit HIV-1 reproduction In MT4 cell cultures. The most active was 5′-hydrogenphosphonate of 3′-azldo-2′,3′-dideoxythymidlne. Equi-molar mixture of all four hydrogenphosphonates is shorn to be less toxic in comparison with each of compounds taken separately.This publication has 5 references indexed in Scilit:
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