RELATIONSHIP BETWEEN BLOOD CHOLESTEROL AND INCREASED METABOLISM FROM DINITROPHENOL AND THYROID 1
Open Access
- 1 July 1934
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 13 (4) , 547-552
- https://doi.org/10.1172/JCI100604
Abstract
From previously reported data, a significant correlation between basal metabolic rate and blood cholesterol concn. was established for man. This correlation was not maintained when the metabolism was raised by dinitrophenol. Therefore, the changes in blood cholesterol in thyroid disease are not related directly to the metabolic rate, but to other actions of thyroid secretion. The stimulation of metabolism by dinitrophenol was as great in patients with initial metabolic rates below [long dash]15% as it was in those with higher rates, which indicates that the drug may increase depressed as well as normal metabolism.Keywords
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