Near-UV Photoproduct(s) of L-Tryptophan: An Inhibitor of Medium-Dependent Repair of X-Ray-Induced Single-Strand Breaks in DNA Which Also Inhibits Replication-Gap Closure in Escherichia coli DNA
- 1 January 1975
- book chapter
- Published by Springer Nature
Abstract
Near-UV photoproducts of L-tryptophan (TP), which are especially toxic for recombination-deficient (rec) mutants, were found to inhibit medium-dependent repair of X-ray-induced single-strand breaks. This inhibitor also slows the rate of closure of replication gaps, suggesting that these two processes may have a common pathway (or share a required step which TP can inhibit).Keywords
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