Partial monosomy or trisomy resulting from crossing over within a rearranged chromosome 1
- 1 November 1976
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 10 (5) , 319-324
- https://doi.org/10.1111/j.1399-0004.1976.tb00055.x
Abstract
Two sibs, both monosomic for the same portion of 1q (q25q32), had similar severe mental and physical retardation. An older sib was trisomic for the same portion of 1q and less severely affected. These partially monosomic and partially trisomic No. 1 chromosomes resulted from meiotic crossover in the mother, who is a balanced heterozygote of the type 46,XX, ins (1) (p32q25q32).This publication has 7 references indexed in Scilit:
- A partial trisomy of chromosome 1 in a family with a t(1q−;4q+) translocationClinical Genetics, 2008
- Presumptive direct insertion within chromosome 2 in manAnnals of Human Genetics, 1973
- INTERSTITIAL TRANSLOCATION IN MANThe Lancet, 1972
- FAMILIAL INSERTIONAL TRANSLOCATIONThe Lancet, 1972
- AN INTERSTITIAL TRANSLOCATION: CHROMOSOME NO. 1p TO 4qThe Lancet, 1972
- Rapid processing of primary embryonic tissues for chromosome banding pattern analysisCytogenetic and Genome Research, 1972
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960