GENERALIZED CYTOMEGALIC INCLUSION DISEASE IN NEONATES AND INFANTS

Abstract
Cytomegalic inclusion disease (CMI) is caused by the salivary gland virus which is species-specific and is characterized by formation of inclusion-bearing cells in various organs. From the viewpoint of spreading, it is divided into the localized and generalized type. Among 18 generalized cases in infants, inclusion-bearing cells were detected in more than 3 organs. As to the portal of entry and the time of infection, CMI can be classified into 3 subgroups in infants; congenital form (2 cases), early acquired form (8 cases) and acquired form with other debilitating diseases (8 cases).